Urinary tract infection (UTI) – adult
Management
Antibiotic treatment is indicated for all people who are symptomatic. Asymptomatic bacteriuria requires antibiotic treatment in women who are pregnant but not in elderly women or patients with long-term indwelling urinary catheters.Non-pregnant females with uncomplicated UTI do not require a urine culture. However, urine culture is recommended in males, women who are pregnant, and those who fail to respond to empiric treatment within two days. Women who are pregnant should have repeat urine culture one to two weeks after completing treatment to ensure cure.
Common pathogens
Escherichia coli, Staphylococcus saprophyticus, Proteus spp., Klebsiella spp., Enterococcus sppAntibiotic for Urinary tract infection in adult
First choice
Trimethoprim
Adult: 300 mg, once daily, for three days (avoid during the first trimester of pregnancy)OR
Nitrofurantoin
Adult: 50 mg, four times daily, for five days (avoid at 36+ weeks in pregnancy, and in significant renal impairment)Treat for seven days in pregnant women and in males
Alternatives
Norfloxacin
Adult: 400 mg, twice daily for three days – but should be reserved for isolates resistant to initial empiric choices and avoided during pregnancyUrinary tract infection (UTI)in children
Management
Refer children aged under three months, those with severe illness, or those with recurrent infection, to hospital. Also consider referral of children aged under six months.Children aged over six months, without renal tract abnormalities, and who do not have acute pyelonephritis, may be treated with a short course (three days) of antibiotics.
All children with suspected UTI should have a urine culture collected as a clean specimen (clean catch, catheter, midstream urine) as it may be a marker for previously undetected renal malformations, particularly in younger children. In older children it can be a marker for bladder and/or bowel dysfunction.
For information on collecting a urine specimen in children, see: “Managing urinary tract infections in children”, BPJ 44 (May, 2012).
Common pathogens
Escherichia coli, Proteus spp., Klebsiella spp., Enterococcus spp.Antibiotic for Urinary tract infection in child
First choice
Co-trimoxazole
Child: 0.5 mL/kg/dose oral liquid (40+200 mg/ 5 mL), twice daily, for three days (maximum 20 mL/dose)If a child can swallow tablets, co-trimoxazole 80+400 mg tablets can be used (one tablet is equivalent to 10 mL of co-trimoxazole oral liquid)
No comments:
Post a Comment