Saturday, 15 April 2017

Urinary tract infection adult and children antibiotic treatment


Urinary tract infection (UTI) – adult   

Management

Antibiotic treatment is indicated for all people who are symptomatic. Asymptomatic bacteriuria requires antibiotic treatment in women who are pregnant but not in elderly women or patients with long-term indwelling urinary catheters.
Non-pregnant females with uncomplicated UTI do not require a urine culture. However, urine culture is recommended in males, women who are pregnant, and those who fail to respond to empiric treatment within two days. Women who are pregnant should have repeat urine culture one to two weeks after completing treatment to ensure cure.  

Common pathogens

Escherichia coli, Staphylococcus saprophyticus, Proteus spp., Klebsiella spp., Enterococcus spp  

Antibiotic for Urinary tract infection in adult   

First choice

Trimethoprim 

Adult: 300 mg, once daily, for three days (avoid during the first trimester of pregnancy)
OR

Nitrofurantoin 

Adult: 50 mg, four times daily, for five days (avoid at 36+ weeks in pregnancy, and in significant renal impairment)
Treat for seven days in pregnant women and in males  

Alternatives

Norfloxacin 

Adult: 400 mg, twice daily for three days – but should be reserved for isolates resistant to initial empiric choices and avoided during pregnancy  

Urinary tract infection (UTI)in children    

Management

Refer children aged under three months, those with severe illness, or those with recurrent infection, to hospital. Also consider referral of children aged under six months.
Children aged over six months, without renal tract abnormalities, and who do not have acute pyelonephritis, may be treated with a short course (three days) of antibiotics.
All children with suspected UTI should have a urine culture collected as a clean specimen (clean catch, catheter, midstream urine) as it may be a marker for previously undetected renal malformations, particularly in younger children. In older children it can be a marker for bladder and/or bowel dysfunction.
For information on collecting a urine specimen in children, see: “Managing urinary tract infections in children”, BPJ 44 (May, 2012).  

Common pathogens

Escherichia coli, Proteus spp., Klebsiella spp., Enterococcus spp.  

Antibiotic for Urinary tract infection in child   

First choice

Co-trimoxazole 

Child: 0.5 mL/kg/dose oral liquid (40+200 mg/ 5 mL), twice daily, for three days (maximum 20 mL/dose)
If a child can swallow tablets, co-trimoxazole 80+400 mg tablets can be used (one tablet is equivalent to 10 mL of co-trimoxazole oral liquid)  

Alternatives

Cefaclor 

Child: 8 – 10 mg/kg/dose, three times daily, for three days (maximum 500 mg/dose)

Amoxicillin clavulanate 

Child: 10 mg/kg/dose (amoxicillin component), three times daily, for three days (maximum 500 mg/dose,amoxicillin component

note the above post is just for education and for general medical information   only if you face such types problem like the above  you should go to the qualified doctor     


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